2. Signaling Pathways
  3. GPCR/G Protein
  4. Vasopressin Receptor
  5. V1b Receptor  Isoform
  6. V1b Receptor  Antagonist

V1b Receptor  Antagonist

V1b Receptor  Antagonists (2):

Cat. No. Product Name Effect Purity
  • HY-15009
    Fuscoside
    		Antagonist ≥98.0%
    Fuscoside (OPC-21268) is an orally effective, nonpeptide, vasopressin V1 receptor antagonist with an IC50 of 0.4 μM.
  • HY-118918
    YM218 free base
    		Antagonist
    YM218 free base is an orally active non-peptide vasopressin (AVP) receptor antagonist. YM218 free base has a high affinity for rat liver V1A receptors with a Ki value of 0.50 nM; it has a lower affinity for rat pituitary V1B, kidney V2, and uterine oxytocin receptors with Ki values of 1510 nM, 72.2 nM, and 150 nM, respectively. YM218 free base can be used in the study of diabetes and kidney disease.